Aromatase Inhibitors: Uses, Dosage, Side Effects, Interactions

Highest levels of aromatase are found in the ovary and placenta, which are the major sources of estrogen in premenopausal women 11. However, aromatase is also found in other tissues, such as liver, kidney, adrenals, brain, muscle and subcutaneous fat where it is also active in producing estrogens, although at low levels 11. These tissues are the major source of estrogen after menopause or oopherectomy. If you have ER-positive breast cancer, aromatase inhibitor therapy significantly reduces your risk that breast cancer will come back.

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Letrozole (Femara) is used treat early breast cancer in women who have experienced menopause and who have had other treatments, such as radiation or surgery to remove the tumor. Letrozole (Femara) is also used to treat early breast cancer in women who have experienced menopause and who have already been treated with a medication called tamoxifen (Nolvadex) for 5 years. Exemestane (Aromasin) is in a class of medications called aromatase inhibitors. Exemestane (Aromasin) works by decreasing the amount of estrogen produced by the body. Exemestane (Aromasin) is also used to treatestrogen sensitive breast cancer in women who have experienced menopause whose breast cancer has worsened while they were winstrol nm 50 mg taking tamoxifen.

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So consuming the two together may increase your risk of developing a liver condition, such as liver failure. Taking a medication with certain vaccines, foods, and other things can affect how the medication works. Simply show the Optum Perks coupon at your preferred pharmacy or order online and instantly save up to 80% without using insurance.

Symptoms of a severe allergic reaction can include swelling under your skin, typically in your eyelids, lips, hands, or feet. They can also include swelling of your tongue, mouth, or throat, which can cause trouble breathing or swallowing. If you develop symptoms of a blood clot, it’s important to contact a doctor right away. Blood clots can be life threatening, and should be treated as soon as possible.

Talk with your doctor about your health history before you take Arimidex. The recommended dosage of Arimidex is one tablet once daily. Very rarely, it’s possible to develop blood clots from taking Arimidex.

• Current aromatase inhibitors (AIs) are considered 3rd generation aromatase inhibitors.
• Aromatase inhibitor therapy has side effects that may affect your quality of life.
• In patients with cirrhosis of the liver, CHild-Pugh Class C, increase the dosing interval to every 48 hours.
• While tamoxifen and aromatase inhibitors both prevent recurrence of estrogen-receptor positive breast cancer, they do work in different ways and for different people.
• The study showed that taking letrozole reduced the risk of dying of breast cancer by 24% to 35%.

Aromatase inhibitors FDA Approved Indications

Your doctor can help answer your questions and determine whether Arimidex is safe for you. It’s not known what side effects Arimidex may cause if taken for bodybuilding or whether the drug could lead to more serious problems if used this way. Its dosage for this use also isn’t known, such as if taken during steroid cycles. Find answers below to some commonly asked questions about Arimidex.